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035 _a(OCoLC)711780324
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037 _a10.1002/9780470656792
_bWiley InterScience
_nhttp://www3.interscience.wiley.com
050 4 _aRS201.S57
_bS63 2011
060 4 _aQV 744
072 7 _aMED
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082 0 4 _a615/.19
_222
049 _aMAIN
245 0 0 _aSolid state characterization of pharmaceuticals /
_cedited by Richard A. Storey, Ingvar Ymen.
260 _aChichester, UK :
_bJohn Wiley & Sons,
_c2011.
300 _a1 online resource
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _adata file
_2rda
380 _aBibliography
505 0 _aFront Matter -- Introduction to the Solid State ₆ Physical Properties and Processes / Ingvar Ym̌n -- X-Ray Diffraction / Chris J Gilmore -- Spectroscopic Characterization / Andrew O'Neil, Howell Edwards -- Thermal Analysis ₆ Conventional Techniques / Mark Saunders, Paul Gabbott -- Thermal Analysis ₆ Dielectric Techniques / Susan Barker, Milan D Antonijevic -- Isothermal Calorimetric Analysis / Andrew Hills -- Calorimetric Methods ₆ Solution Calorimetry / Simon Gaisford -- Vapour Sorption and Surface Analysis / Jerry Y Y Heng, Daryl R Williams -- Microscopy / Gary Nichols, Shen Luk, Clive Roberts -- Particulate Analysis ₆ Mechanical Properties / Ron J Roberts -- Particulate Analysis ₆ Particle Size / Xian-Ming Zeng -- Computational Polymorph Prediction / Sarah L Price, Louise S Price -- Patenting of Inventions Relating to Polymorphs / Bertrand Gellie, Claire Johnson, Thomas Weisbrod -- A ₁Roadmap₂ to Solid Form Selection / Richard Storey -- Index.
504 _aIncludes bibliographical references and index.
505 0 _aIntroduction to the solid state : physical properties and processes -- X-ray diffraction -- Spectroscopic characterisation -- Dielectric spectroscopy and thermally stimulated current spectroscopy : use in the characterisation of solid state pharmaceutical systems -- Solid state characterisation of pharmaceuticals -- Calorimetric methods : solution calorimetry -- Vapour sorption for bulk and surface analysis -- Microscopy -- Mechanical properties of pharmaceutical materials -- Particle size assessment -- Computational polymorph prediction -- Patenting of inventions relating to polymorphs -- A 'roadmap' to solid form selection.
520 _aThe field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balance.
588 0 _aPrint version record.
650 0 _aSolid dosage forms.
650 0 _aDrugs
_xDesign.
650 0 _aPharmaceutical chemistry.
650 2 _aChemistry, Pharmaceutical.
650 2 _aDrug Design.
650 2 _aPharmaceutical Preparations
_xchemistry.
650 4 _aPharmacy.
650 4 _aMedicine.
650 7 _aMEDICAL
_xDrug Guides.
_2bisacsh
650 7 _aMEDICAL
_xNursing
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPharmacy.
_2bisacsh
650 7 _aDrugs
_xDesign.
_2fast
_0(OCoLC)fst00898790
650 7 _aPharmaceutical chemistry.
_2fast
_0(OCoLC)fst01060115
650 7 _aSolid dosage forms.
_2fast
_0(OCoLC)fst01125411
655 4 _aElectronic books.
700 1 _aStorey, Richard A.
700 1 _aYmen, Ingvar.
776 0 8 _iPrint version:
_tSolid state characterization of pharmaceuticals.
_dChichester, UK : John Wiley & Sons, 2011
_z9781405134941
_w(DLC) 2010053725
_w(OCoLC)694600439
856 4 0 _uhttp://onlinelibrary.wiley.com/book/10.1002/9780470656792
_zWiley Online Library
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