Innate immune system of skin and oral mucosa : properties and impact in pharmaceutics, cosmetics, and personal care products / [edited] by Nava Dayan, Philip W. Wertz.

Frontmatter -- Color Plates -- Overview of Skin and Mucosal Innate Immunity: History, Ethics, and Science. Germ Free: Hygiene History and Consuming Antimicrobial and Antiseptic Products / Jennifer Tebbe-Grossman, Martha N Gardner -- Ethical Responsibilities in Formulating, Marketing, and Using Antimicrobial Personal Products / Kenneth A Richman -- Role of Stratum Corneum in Permeability Barrier Function and Antimicrobial Defense / Peter M Elias -- Antimicrobial Lipids and Peptides. Antimicrobial Lipids of the Skin and Oral Mucosa / Kim A Brogden, David R Drake, Deborah V Dawson, Jennifer R Hill, Carol L Bratt, Philip W Wertz -- Resident Microflora and Antimicrobial Peptides of Skin / Shamim A Ansari -- Defensins / Neelam Muizzudin -- Antimicrobial Peptides of Skin and Oral Mucosa / Whasun O Chung, Henrik Dommisch -- Vernix Caseosa and Innate Immunity / Steven B Hoath, Vivek Narendran, Marty O Visscher -- Host Cellular Components of Innate Immunity. Sentinel Role of Mast Cells in Innate Immunity / Zhenping Wang, Anna Di Nardo -- Cellular Immunity of the Skin: Langerhans Cells and Dendritic Cells / Karen E Burke, Niroshana Anandasabapathy -- Innate Immunity Response to Stress and Aging. Changes in Skin Immunity with Age and Disease / Barbara Geusens, Ilse Mollet, Chris D Anderson, Sarah Terras, Michael S Roberts, Jo Lambert -- Epidermis as a Shield from Radiation and Oxidative Stress / Giuseppe Valacchi -- The Impact on the Skin's Innate Immunity by Cosmetic Products Applied to the Skin and Scalp / Rudranath Persaud, Thomas Re -- UV-Induced Immunosuppression of Skin / Roger L McMullen -- Innate Immunity Microbial Challenges. Deranged Antimicrobial Barrier in Atopic Dermatitis: Roles of Sphingosine, Hexadecenoic Acid, and Beta-Defensine-2 / Gengi Imokawa -- Resident Microflora of the Skin and Oral Mucosa / David R Drake -- Species and their Role in the Generation of Human Malodor / Carol L Bratt, Nava Dayan -- Index.

Includes bibliographical references.

Historical overview of the use of soaps and cleaning products / Jennifer Tebbe-Grossman and Martha N. Gardner -- Ethical responsibilities in formulating, marketing, and using antimicrobial products / Kenneth Richman -- Stratum corneum structural and functional contributions to cutaneous antimicrobial defense / Peter Elias -- Antimicrobial lipids of the skin and oral mucosa / K.A. Brogden [and others] -- Resident microflora and antimicrobial peptides of skin / Shamim Ansari -- Diffensins / Neelam Muizzudin -- Antimicrobial peptides of skin and oral mucosa / Whasun Oh Chung and Henrik Dommisch -- Vernix caseosa and innate immunity / Steven B. Hoath, Vivek Narendran, Marty O. Visscher -- Sentinel role of mast cells in innate immunity / Zhenping Wang, Anna Di Nardo -- Cellular immunity of the skin : langerhans cells and dendritic cells / Karen E. Burke and Niroshana Anandasabapathy -- Changes in skin immunity with age and disease / Barbara Geusens [and others] -- Epidermis as a shield from radiation and oxidative stress / Giuseppe Valacchi -- The impact to skin's innate immunity by cosmetic products applied to skin and scalp / Rudranath Persaud and Thomas Re -- UV induced immunosuppression of skin / Roger L. McMullen -- Deranged anti-microbial barrier in atopic dermatitis : roles of sphingosine, hexadecenoic acid and beta-defensine-2 / Gengi Imokawa -- Resident microflora of skin and oral mucosa / David Drake -- Corynebacterium species and their role in the generation of human malodor / Carol Bratt and Nava Dayan.

An in-depth look at cutting-edge research on the body's innate immune system Innate immunity is the body's first line of protection against potential microbial, viral, and environmental attacks, and the skin and oral mucosa are two of the most powerful barriers that which we rely on to stay well. The definitive book on the subject, Innate Immune System of Skin and Oral Mucosa: Properties and Impact in Pharmaceutics, Cosmetics, and Personal Care Products provides a comprehensive overview of these systems, including coverage of antimicrobial peptides and lipids and microbial challenges and stressors that can influence innate immunity. Designed to help experts and newcomers alike in fields like dermatology, oral pathology, cosmetics, personal care, and pharmaceuticals, the book is filled with suggestions to assist research and development. Looking at the many challenges facing the innate immune system, including the impact of topically applied skin products and medications, Innate Immune System of Skin and Oral Mucosa paves the way for next generation treatment avenues, preventative approaches, and drug development.

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