Forward-Time Population Genetics Simulations : Methods, Implementation, and Applications / Bo Peng, Marek Kimmel, Christopher I. Amos.

Includes bibliographical references and index.

Frontmatter -- Basic Concepts and Models -- Simulation of Population Genetics Models -- Ascertainment Bias in Population Genetics -- Observing Properties of Evolving Populations -- Simulating Populations with Complex Human Diseases -- Nonrandom Mating and its Applications -- Appendix: Forward-Time Simulations Using simuPOP -- Index.

Basic concepts and models -- Simulation of population genetics models -- Ascertainment bias in population genetics -- Observing properties of evolving populations -- Simulating populations with complex human diseases -- Nonrandom mating and its applications.

The rapid increase of the power of personal computers has led to the use of serious simulation programs such as easy POP in genetic studies. This book summarizes recent advances in forward-time simulation methods and demonstrates their applications in population genetics and genetic epidemiology. The authors introduce commonly used forward-time population genetics simulation methods, including some new methods, and introduce a forward-time population genetics simulation environment, simuPOP, as a powerful and flexible tool to implement these simulations. Researchers and students in population and statistical genetics will find this book useful.