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Developmental toxicology [electronic resource].

Contributor(s): Material type: TextTextSeries: Target organ toxicology series ; v. 27Publication details: New York : Informa Healthcare, c2009.Edition: 3rd ed. / edited by Deborah K. Hansen, Barbara D. AbbottDescription: x, 384 p., [8] p. of plates : ill. (some col.)ISBN:
  • 9781420054385 (ebook : PDF)
Subject(s): Genre/Form: Additional physical formats: No titleOnline resources: Available additional physical forms:
  • Also available in print edition
Contents:
1. Role of apoptosis in normal and abnormal development / Philip Mirkes -- 2. Signal transduction pathways as targets for teratogens / Barbara D. Abbott -- 3. Nutrition in developmental toxicology / Deborah K. Hansen -- 4. Epigenetic mechanisms : role of DNA methylation, histone modifications, and imprinting / Robert G. Ellis-Hutchings and John M. Rogers -- 5. Personalized nutrition and medicine in perinatal development / Jim Kaput, James J. Chen, and William Slikker, Jr. -- 6. Targeted gene changes affecting developmental toxicity / Sid Hunter and Phillip Hartig -- 7. Use of mammalian in vitro systems, including embryonic stem cells, in developmental toxicity testing / Terence R.S. Ozolin�s -- 8. Zebrafish : a nonmammalian model of developmental toxicology / Kimberly C. Brannen ... [et al.] -- 9. Physiologically based pharmacokinetic modeling in the risk assessment of developmental toxicants / Mathieu Valcke and Kannan Krishnan -- 10. Integration of whole animal developmental toxicity data into risk assessment / Mark E. Hurtt and Gregg D. Cappon -- 11. Genomic approaches in developmental toxicology / George P. Daston and Jorge M. Naciff -- 12. Comparative bioinformatics and computational toxicology / Thomas B. Knudsen and Robert J. Kavlock -- 13. Investigating drug effects in human pregnancy / Christina D. Chambers
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Includes bibliographical references and index.

1. Role of apoptosis in normal and abnormal development / Philip Mirkes -- 2. Signal transduction pathways as targets for teratogens / Barbara D. Abbott -- 3. Nutrition in developmental toxicology / Deborah K. Hansen -- 4. Epigenetic mechanisms : role of DNA methylation, histone modifications, and imprinting / Robert G. Ellis-Hutchings and John M. Rogers -- 5. Personalized nutrition and medicine in perinatal development / Jim Kaput, James J. Chen, and William Slikker, Jr. -- 6. Targeted gene changes affecting developmental toxicity / Sid Hunter and Phillip Hartig -- 7. Use of mammalian in vitro systems, including embryonic stem cells, in developmental toxicity testing / Terence R.S. Ozolin�s -- 8. Zebrafish : a nonmammalian model of developmental toxicology / Kimberly C. Brannen ... [et al.] -- 9. Physiologically based pharmacokinetic modeling in the risk assessment of developmental toxicants / Mathieu Valcke and Kannan Krishnan -- 10. Integration of whole animal developmental toxicity data into risk assessment / Mark E. Hurtt and Gregg D. Cappon -- 11. Genomic approaches in developmental toxicology / George P. Daston and Jorge M. Naciff -- 12. Comparative bioinformatics and computational toxicology / Thomas B. Knudsen and Robert J. Kavlock -- 13. Investigating drug effects in human pregnancy / Christina D. Chambers

Also available in print edition

Mode of access: World Wide Web

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