Human Population Genetics.

Cover; Series Page; Title Page; Copyright; Foreword; Preface; What are We Doing Here?; Format and Organization of the Book; Acknowledgments; Chapter 1: Genetic, Mathematical, and Anthropological Background; 1.1 The Scope of Population Genetics; 1.2 Genetics Background; 1.3 Principles of Probability; 1.4 The Anthropological Connection; 1.5 A Closing Thought; Chapter 2: Hardy-Weinberg Equilibrium; 2.1 Genotype And Allele Frequencies; 2.2 What is Hardy-Weinberg Equilibrium?; 2.3 The Mathematics of Hardy-Weinberg Equilibrium; 2.4 Using Hardy-Weinberg Equilibrium.

2.5 Extensions of Hardy-Weinberg Equilibrium; 2.6 Hardy-Weinberg Equilibrium and Evolution; 2.7 Summary; Appendix 2.1 Proof Showing How Allele Frequencies can be Computed from Genotype Frequencies; Appendix 2.2 Using the Chi-Square Statistic to Test for Hardy-Weinberg Equilibrium; Chapter 3: Inbreeding; 3.1 Quantifying Inbreeding; 3.2 Population Genetics and Inbreeding; 3.3 Inbreeding in Human Populations; 3.4 Summary; Chapter 4: Mutation; 4.1 The Nature of Mutations; 4.2 Models of Mutation; 4.3 Mutational History and Anthropological Questions; 4.4 Summary.

Appendix 4.1 Use of A Recurrence Relation to Solve Iterative Equations; Chapter 5: Genetic Drift; 5.1 What is Genetic Drift?; 5.2 Genetic Drift and Population Size; 5.3 Effects on Genetic Variation; 5.4 Mutation and Genetic Drift; 5.5 Coalescent Theory; 5.6 Summary; Appendix 5.1 Decay of Heterozygosity Over Time Due to Genetic Drift; Appendix 5.2 Expected Heterozygosity at Equilibrium in the Infinite Alleles Model; Appendix 5.3 Computation of Nucleotide Diversity; Chapter 6: Models of Natural Selection; 6.1 How Does Natural Selection Work?; 6.2 A General Model of Natural Selection.

6.3 Types of Natural Selection; 6.4 Other Aspects of Selection; 6.5 Summary; Appendix 6.1 Derivation of the Amount of Change in Allele Frequencies per Generation for A General Model of Natural Selection; Appendix 6.2 Derivation of Formulas for Selection against the Recessive Homozygote; Appendix 6.3 Derivation of Formulas for Selection Against Dominant Alleles; Appendix 6.4 Derivation of Formulas for Selection with Codominant Alleles; Appendix 6.5 Derivation of Formulas for Selection Against the Heterozygote; Appendix 6.6 Derivation of Formulas for Selection for the Heterozygote.

Appendix 6.7 Calculus-Based Derivation of the Equilibrium Allele Frequency under Selection for the Heterozygote; Appendix 6.8 Mutation-Selection Equilibrium under Selection Against A Recessive Allele; Appendix 6.9 Mutation-Selection Equilibrium under Selection Against A Dominant Allele; Chapter 7: Natural Selection In Human Populations; 7.1 Case Studies of Natural Selection in Human Populations; 7.2 Are Humans Still Evolving?; 7.3 Summary; Chapter 8: Gene Flow; 8.1 The Evolutionary Impact of Gene Flow; 8.2 Models of Gene Flow; 8.3 Gene Flow and Genetic Drift.

8.4 Estimating Admixture in Human Populations.

Introductory guide to human population genetics and microevolutionary theory. Providing an introduction to mathematical population genetics, Human Population Genetics gives basic background on the mechanisms of human microevolution. This text combines mathematics, biology, and anthropology and is best suited for advanced undergraduate and graduate study. Thorough and accessible, Human Population Genetics presents concepts and methods of population genetics specific to human population study, utilizing uncomplicated mathematics like high school algebra and basic concepts of probability to explain.

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