Polypharmacology in drug discovery / (Record no. 11697)
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| fixed length control field | 07179cam a2200961Ia 4500 |
| 001 - CONTROL NUMBER | |
| control field | ocn779410061 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20171224113852.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cnu---unuuu |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 120306s2012 njua ob 001 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | N$T |
| Language of cataloging | eng |
| Description conventions | pn |
| Transcribing agency | N$T |
| Modifying agency | UIU |
| -- | DG1 |
| -- | YDXCP |
| -- | CDX |
| -- | IUL |
| -- | OCLCQ |
| -- | MYG |
| -- | E7B |
| -- | COO |
| -- | NLGGC |
| -- | OCLCF |
| -- | RECBK |
| -- | NLE |
| -- | MHW |
| -- | IDEBK |
| -- | OCLCQ |
| -- | D6H |
| -- | OCLCQ |
| -- | AZK |
| 019 ## - | |
| -- | 784124194 |
| -- | 811493986 |
| -- | 839336010 |
| -- | 860514925 |
| -- | 898985525 |
| -- | 961529870 |
| -- | 962708756 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781118098141 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1118098145 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781118098127 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1118098129 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781280589324 |
| Qualifying information | (MyiLibrary) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1280589329 |
| Qualifying information | (MyiLibrary) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781118098134 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1118098137 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 9780470590904 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Cancelled/invalid ISBN | 0470590904 |
| 028 01 - PUBLISHER NUMBER | |
| Publisher number | EB00062625 |
| Source | Recorded Books |
| 029 1# - (OCLC) | |
| OCLC library identifier | AU@ |
| System control number | 000049014066 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DEBBG |
| System control number | BV042794916 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DEBBG |
| System control number | BV043394309 |
| 029 1# - (OCLC) | |
| OCLC library identifier | DKDLA |
| System control number | 820120-katalog:000600378 |
| 029 1# - (OCLC) | |
| OCLC library identifier | NLGGC |
| System control number | 340803193 |
| 029 1# - (OCLC) | |
| OCLC library identifier | NZ1 |
| System control number | 14976855 |
| 029 1# - (OCLC) | |
| OCLC library identifier | ZWZ |
| System control number | 17893285X |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)779410061 |
| Canceled/invalid control number | (OCoLC)784124194 |
| -- | (OCoLC)811493986 |
| -- | (OCoLC)839336010 |
| -- | (OCoLC)860514925 |
| -- | (OCoLC)898985525 |
| -- | (OCoLC)961529870 |
| -- | (OCoLC)962708756 |
| 037 ## - SOURCE OF ACQUISITION | |
| Stock number | 10.1002/9781118098141 |
| Source of stock number/acquisition | Wiley InterScience |
| Note | http://www3.interscience.wiley.com |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM301.25 |
| Item number | .P65 2012eb |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | QV 744 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 023000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 058170 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 071000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 072000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615.19 |
| Edition number | 23 |
| 084 ## - OTHER CLASSIFICATION NUMBER | |
| Classification number | 44.42 |
| Source of number | bcl |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | MAIN |
| 245 00 - TITLE STATEMENT | |
| Title | Polypharmacology in drug discovery / |
| Statement of responsibility, etc | edited by Jens-Uwe Peters. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Hoboken, N.J. : |
| Name of publisher, distributor, etc | Wiley, |
| Date of publication, distribution, etc | ©2012. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xxiii, 510 pages) : |
| Other physical details | illustrations |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 347 ## - | |
| -- | data file |
| -- | rda |
| 380 ## - | |
| -- | Bibliography |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | "Covers the two-sided nature of polypharmacology--its contribution to adverse drug reactions and its benefit in certain therapeutic drug classes. Addresses the important topic of polypharmacology in drug discovery, a subject that has not been thoroughly covered outside of scattered journal articles. Overviews state-of-the-art approaches and developments to help readers understand concepts and issues related to polypharmacology."-- |
| -- | Provided by publisher. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Frontmatter -- Color Plates -- Introduction: The Case for Polypharmacology / Andrew L Hopkins -- Polypharmacology: A Safety Concern in Drug Discovery. The Relevance of Off-Target Polypharmacology / Bruce D Car -- Screening for Safety-Relevant Off-Target Activities / Laszlo Urban, Steven Whitebread, Jacques Hamon, Dmitri Mikhailov, Kamal Azzaoui -- Pharmacological Promiscuity and Molecular Properties / Jens-Uwe Peters -- Kinases as Antitargets in Genotoxicity / Stephan Kirchner -- Activity at Cardiovascular Ion Channels: A Key Issue for Drug Discovery / Ian M Bell, Mark T Bilodeau, Armando A Lagrutta -- Prediction of Side Effects Based on Fingerprint Profiling and Data Mining / Jacques Migeon -- Polypharmacology: An Opportunity for Drug Discovery. Polypharmacological Drugs: ₃Magic Shotguns₄ for Psychiatric Diseases / Wesley K Kroeze, Bryan L Roth -- Polypharmacological Kinase Inhibitors: New Hopes for Cancer Therapy / Annalisa Petrelli -- Polypharmacology as an Emerging Trend in Antibacterial Discovery / Lynn L Silver -- A ₃Magic Shotgun₄ Perspective on Anticonvulsant Mechanisms / Matt T Bianchi, Kathy Chuang -- Selective Optimization of Side Activities (SOSA): A Promising way for Drug Discovery / Thierry Langer, Camille-Georges Wermuth -- Selected Approaches to Polypharmacological Drug Discovery. Selective Multitargeted Drugs / Richard Morphy -- Computational Multitarget Drug Discovery / Jeremy A Horst, Adrian Laurenzi, Brady Bernard, Ram Samudrala -- Behavior-Based Screening as an Approach to Polypharmacological Ligands / Dani Brunner, Vadim Alexandrov, Barbara Caldarone, Taleen Hanania, David Lowe, Jeff Schneider, Jayaraman Chandrasekhar -- Multicomponent Therapeutics / Alexis A Borisy, Grant R Zimmermann, Joseph Leh̀r -- Case Studies. Discovery of Sunitinib as a Multitarget Treatment of Cancer / Catherine Delbaldo, Camelia Colichi, Marie-Paule Sablin, Chantal Dreyer, Bertrand Billemont, Sandrine Faivre, Eric Raymond -- Antipsychotics / Claus Riemer -- Triple-Uptake Inhibitors (Broad-Spectrum Antidepressants) / Phil Skolnick -- Therapeutic Potential of Small Molecules Modulating the Cyclooxygenase₆5-Lipoxygenase Pathway / Wolfgang Albrecht, Stefan Laufer -- Drug Research Leading to Imatinib and beyond to Nilotinib / Paul W Manley, Jorg Zimmermann -- Towards Antimalarial Hybrid Drugs / Bernard Meunier -- Multitargeted Drugs for Treatment of Alzheimer's Disease / Andrea Cavalli, Maria Laura Bolognesi -- Carbonic Anhydrases: Off Targets, Add-On Activities, or Emerging Novel Targets? / Claudiu T Supuran -- Index. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | "An essential outline of the main facets of polypharmacology in drug discovery research. Extending drug discovery opportunities beyond the "one drug, one target" philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of polypharmacology and how it can be applied as an innovative concept for developing medicines for treating bacterial infections, epilepsy, cancer, psychiatric disorders, and more."-- |
| -- | Provided by publisher. |
| 588 0# - | |
| -- | Print version record. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug development. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drugs |
| General subdivision | Toxicology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmacology. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Medical. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Drug Guides. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Nursing |
| -- | Pharmacology. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Pharmacology. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Pharmacy. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug development. |
| Source of heading or term | fast |
| -- | (OCoLC)fst00898670 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drugs |
| General subdivision | Toxicology. |
| Source of heading or term | fast |
| -- | (OCoLC)fst00898958 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmacology. |
| Source of heading or term | fast |
| -- | (OCoLC)fst01060259 |
| 650 12 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug Discovery. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug Toxicity. |
| 650 22 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmaceutical Preparations |
| General subdivision | chemistry. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Peters, Jens-Uwe. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| Title | Polypharmacology in drug discovery. |
| Place, publisher, and date of publication | Hoboken, N.J. : Wiley, ©2011 |
| International Standard Book Number | 9780470590904 |
| Record control number | (DLC) 2011052324 |
| -- | (OCoLC)714728070 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://onlinelibrary.wiley.com/book/10.1002/9781118098141">http://onlinelibrary.wiley.com/book/10.1002/9781118098141</a> |
| Public note | Wiley Online Library |
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| -- | Ingram Digital eBook Collection |
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| -- | Recorded Books, LLC |
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