Systems biology in drug discovery and development / (Record no. 11300)
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| 001 - CONTROL NUMBER | |
| control field | ocn755168864 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20171224113722.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION | |
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| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
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| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 101013s2011 nju ob 000 0 eng d |
| 010 ## - LIBRARY OF CONGRESS CONTROL NUMBER | |
| Canceled/invalid LC control number | 2010043475 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | CDX |
| Language of cataloging | eng |
| Description conventions | pn |
| Transcribing agency | CDX |
| Modifying agency | OCLCQ |
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| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780470261231 |
| Qualifying information | (Cloth) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0470261234 |
| Qualifying information | (Cloth) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781118016435 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1118016432 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781118016411 |
| Qualifying information | (electronic bk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1118016416 |
| Qualifying information | (electronic bk.) |
| 024 8# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 9786613273697 |
| 029 1# - (OCLC) | |
| OCLC library identifier | AU@ |
| System control number | 000049552126 |
| 029 1# - (OCLC) | |
| OCLC library identifier | AU@ |
| System control number | 000053284770 |
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| OCLC library identifier | DKDLA |
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| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)755168864 |
| Canceled/invalid control number | (OCoLC)759992602 |
| -- | (OCoLC)768204517 |
| -- | (OCoLC)808669812 |
| -- | (OCoLC)961497485 |
| -- | (OCoLC)962671123 |
| -- | (OCoLC)966213828 |
| 037 ## - SOURCE OF ACQUISITION | |
| Stock number | 327369 |
| Source of stock number/acquisition | MIL |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RM301.25 |
| Item number | .S97 2011eb |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | QV 744 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MM |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 023000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 058170 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 071000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 072000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 615/.19 |
| Edition number | 22 |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | MAIN |
| 245 00 - TITLE STATEMENT | |
| Title | Systems biology in drug discovery and development / |
| Statement of responsibility, etc | edited by Daniel L. Young, Seth Michelson. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc | Hoboken, N.J. : |
| Name of publisher, distributor, etc | Wiley, |
| Date of publication, distribution, etc | 2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource. |
| 336 ## - | |
| -- | text |
| -- | txt |
| -- | rdacontent |
| 337 ## - | |
| -- | computer |
| -- | c |
| -- | rdamedia |
| 338 ## - | |
| -- | online resource |
| -- | cr |
| -- | rdacarrier |
| 490 1# - SERIES STATEMENT | |
| Series statement | Wiley series on technologies for the pharmaceutical industry |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Includes bibliographical references. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc | This is the first comprehensive systems biology book to focus on its applications in drug discovery and development. Using real-world examples, the book shows how systems biology can be used to enhance pharmaceutical research and drug development. It highlights essential components of drug discovery like target identification and validation and complementary systems approaches like text-mining, large multi-context datasets and regression modeling. It also provides models for treatment personalization and methods for applying systems biology to pharmacokinetics, pharmacodynamics, and candidate biomarker indentification. Introducing key methods and technical approaches the book addresses the challenges currently facing the drug industry. |
| 588 0# - | |
| -- | Print version record. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Frontmatter -- Color Plates -- Introduction to Systems Biology in Approach. Introduction to Systems Biology in Drug Discovery and Development / Seth Michelson, Daniel L Young -- Methods for Biology: Model Construction and Analysis / Theresa Yuraszeck, Peter Chang, Kalyan Gayen, Eric Kwei, Henry Mirsky, Francis J Doyle -- Methods in Biology: Modeling Feedback Dynamics in Pathways / Peter Wellstead, Olaf Wolkenhauer -- Simulation of Population Variability in Pharmacokinetics / Jiansong Yang -- Applications to Drug Discovery. Applications of Systems Biology Approaches to Target Identification and Validation in Drug Discovery / Bart S Hendriks -- Lead Identification and Optimization / Seth Michelson -- Role of Core Biological Motifs in Dose₆Response Modeling: An Example with Switchlike Circuits / Sudin Bhattacharya, Qiang Zhang, Melvin E Andersen -- Mechanism-Based Pharmacokinetic₆Pharmacodynamic Modeling During Discovery and Early Development / Hans Peter Grimm, Ying Ou, Micaela Reddy, Pascale David-Pierson, Thierry Lav̌ -- Applications to Drug Development. Developing Oncology Drugs Using Virtual Patients of Vascular Tumor Diseases / Zvia Agur, Naamah Bloch, Boris Gorelik, Marina Kleiman, Yuri Kogan, Yael Sagi, D Sidransky, Yael Ronen -- Systems Modeling Applied to Candidate Biomarker Identification / Ananth Kadambi, Daniel L Young, Kapil Gadkar -- Simulating Clinical Trials / Tom Parke -- Synergies with other Technologies. Pathway Analysis in Drug Discovery / Anton Yuryev -- Functional Mapping for Predicting Drug Response and Enabling Personalized Medicine / Yao Li, Wei Hou, Wei Zhao, Kwangmi Ahn, Rongling Wu -- Future Outlook for Systems Biology / Daniel L Young, Seth Michelson -- Index. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Introduction to systems biology in drug discovery and development -- Methods for in silico biology : model construction and analysis -- Methods in in silico biology : modeling feedback dynamics in pathways -- Simulation of population variability in pharmacokinetics -- Applications of systems biology approaches to target identification and validation in drug discovery -- Lead identification and optimization -- The role of core biological motifs in dose-response modeling : an example with switch-like circuits -- Mechanism based pharmacokinetic-pharmacodynamic modeling during discovery and early development -- Developing oncology drugs using virtual patients of vascular tumor diseases -- Systems modeling applied to candidate biomarker identification -- Simulating clinical trials -- Pathway analysis in drug discovery -- Functional mapping for predicting drug response and enabling personalized medicine -- Future outlook of systems biology. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug development. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Systems biology. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Drug Guides. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Nursing |
| -- | Pharmacology. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Pharmacology. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | MEDICAL |
| General subdivision | Pharmacy. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug development. |
| Source of heading or term | fast |
| -- | (OCoLC)fst00898670 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Systems biology. |
| Source of heading or term | fast |
| -- | (OCoLC)fst01745552 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Drug Discovery |
| General subdivision | methods. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Models, Biological. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmacokinetics. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Pharmacological Phenomena. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Systems Biology |
| General subdivision | methods. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 655 #7 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| Source of term | local |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Young, Daniel L., |
| Relator term | editor. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Michelson, Seth, |
| Relator term | editor. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Display text | Print version: |
| International Standard Book Number | 9786613273697 |
| Record control number | (DLC) 2010043475 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Wiley series on technologies for the pharmaceutical industry. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="http://onlinelibrary.wiley.com/book/10.1002/9781118016435">http://onlinelibrary.wiley.com/book/10.1002/9781118016435</a> |
| Public note | Wiley Online Library |
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