Quantitative drug design
Martin, Yvonne Connolly, 1936-
Quantitative drug design a critical introduction / [electronic resource] : Yvonne Connolly Martin. - 2nd ed. - Boca Raton : CRC Press/Taylor & Francis, c2010. - xv, 282 p. : ill.
Includes bibliographical references and index.
Overview of quantitative drug design -- Noncovalent interactions in biological systems -- Preparation of 3D structures of molecules for 3D QSAR -- Calculating physical properties of molecules -- Biological data -- Form of equations that relate potency and physical properties -- Statistical basis of regression and partial least-squares analysis -- Strategy for the statistical evaluation of a data set of related molecules -- Detailed examples of QSAR calculations on erythromycin esters -- Case studies -- Methods to approach other structure-activity problems.
Mode of access: World Wide Web.
9781420071009 (ebook : PDF)
Drugs--Structure-activity relationships.
QSAR (Biochemistry)
Drugs--Design.
Electronic books.
Quantitative drug design a critical introduction / [electronic resource] : Yvonne Connolly Martin. - 2nd ed. - Boca Raton : CRC Press/Taylor & Francis, c2010. - xv, 282 p. : ill.
Includes bibliographical references and index.
Overview of quantitative drug design -- Noncovalent interactions in biological systems -- Preparation of 3D structures of molecules for 3D QSAR -- Calculating physical properties of molecules -- Biological data -- Form of equations that relate potency and physical properties -- Statistical basis of regression and partial least-squares analysis -- Strategy for the statistical evaluation of a data set of related molecules -- Detailed examples of QSAR calculations on erythromycin esters -- Case studies -- Methods to approach other structure-activity problems.
Mode of access: World Wide Web.
9781420071009 (ebook : PDF)
Drugs--Structure-activity relationships.
QSAR (Biochemistry)
Drugs--Design.
Electronic books.